Reacción #609528

Ecuación de reacción

Sodium carboxylate

sodium 2-trifluoromethylbicyclo[2,2,1]hepta-5-ene-2-carboxylate

triphenylsulfonium chloride

→

objective material

Rendimiento 40.0%

triphenylsulfonium 2-trifluoromethylbicyclo[2,2,1]hepta-5-ene-2-carboxylate

Rendimiento 40.0%

Disolventes

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe organic layer was separated
2. 2
   Extracciónthe aqueous layer was extracted with CH2Cl2
3. 3
   Lavadothe combined organic layers were washed three times with H2O
4. 4
   workup.DISTILLATIONThe solvent was distilled off under reduced pressure

Procedimiento

Sodium carboxylate (21) obtained in (Synthesis Example 1-1-2) was dissolved in 20 g of methylene chloride, 40 g of an aqueous solution of triphenylsulfonium chloride (22) was added to the solution and the resulting mixture was stirred for 30 minutes. The organic layer was separated, the aqueous layer was extracted with CH2Cl2, and the combined organic layers were washed three times with H2O. The solvent was distilled off under reduced pressure to obtain 4.6 g of the objective material, onium salt (Q-1) (Yield: 40%).

Fuente