Reacción #60848
ord-11584843d86f457b87c65f17ad485d99
Ecuación de reacción
(3-bromophenyl)(isocyano)methyl 4-methylphenyl sulfone
N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine
Intermediate 16
N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine
Intermediate 57
(3-bromophenyl)(isocyano)methyl 4-methylphenyl sulfone
intermediate 14
N-(3,4Dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine
→
Reactantes
(3-bromophenyl)(isocyano)methyl 4-methylphenyl sulfone
—
Foam
N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine
Intermediate 16
N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine
Intermediate 57
(3-bromophenyl)(isocyano)methyl 4-methylphenyl sulfone
intermediate 14
N-(3,4Dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine
Reactivos
Ninguno
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
The title compound was prepared by a similar process to that described for Example 6 but using N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine (Intermediate 16) in place of N-(3,4Dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine (intermediate 14) and using ((3-bromophenyl)(isocyano)methyl 4-methylphenyl sulfone (Intermediate 57) in place of PhTosMIC. Foam (1.9 g, 91%);