Reacción #6024

Ecuación de reacción

methyl 4-hydroxy-3-propenylbenzoate

potassium carbonate

allyl bromide

→

title compound

Rendimiento 87.0%

methyl 3-(2-propen-1-yl)-4-(2-propen-1-yloxy)benzoate

Rendimiento 87.0%

Disolventes

acetone

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe mixture was filtered through Celite
2. 2
   Lavadothe filter cake was washed with more acetone and dichloromethane
3. 3
   OtroAfter removing the solvents
4. 4
   workup.DISTILLATIONthe resulting oil was distilled under high vacuum

Procedimiento

A solution of 3.04 g (15.8 mmol) of methyl 4-hydroxy-3-propenylbenzoate (Example 42, Step B) was refluxed with anhydrous potassium carbonate (4.37 g, 2 equiv) and allyl bromide (3.5 mL, 2.5 equiv) in acetone overnight. The mixture was filtered through Celite and the filter cake was washed with more acetone and dichloromethane. After removing the solvents, the resulting oil was distilled under high vacuum to give 3.2 g (87%) of the title compound.

Fuente