Reacción #592532

Ecuación de reacción

ethyl 3-(4-pyrimidinyl)-3-oxopropionate

6,6-dimethyl-1,4,5,6-tetrahydro-pyrimidin-2-ylamine hydrobromide

→

8,8-Dimethyl-2-(pyrimidin-4-yl)-6,7,8,9-tetrahydro-pyrimido[1,2-a]pyrimidin-4-one

Condiciones de reacción

Tratamiento posterior

1. 1
   Otro(prepared by analogy to the method

Procedimiento

A mixture of 2.39 g (12.31 mmol) of ethyl 3-(4-pyrimidinyl)-3-oxopropionate, (prepared by analogy to the method described in patent DE 2705582), 2.33 g (11.19 mmol) 6,6-dimethyl-1,4,5,6-tetrahydro-pyrimidin-2-ylamine hydrobromide

Fuente