Reacción #59024

Ecuación de reacción

hydrochloric acid

Lithium hydroxide monohydrate

4-ethoxycarbonyl-2-methoxyphenylboronic acid

water

→

title compound

Rendimiento 81.7%

4-Carboxy-2-methoxyphenylboronic acid

Rendimiento 81.7%

Disolventes

1,4-dioxane

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrothe solvent was evaporated under reduced pressure
2. 2
   LavadoThe residue was washed with water

Procedimiento

Lithium hydroxide monohydrate (0.092 g) was added to a mixture of 4-ethoxycarbonyl-2-methoxyphenylboronic acid (0.049 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. 2 mol/L hydrochloric acid (1.09 mL) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.035 g).

Fuente