Reacción #58816

Ecuación de reacción

2-(4-Fluorophenoxy)ethylamine

(7-Hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-carbamic acid phenyl ester

water

→

N-[2-(4-Fluorophenoxy)ethyl]-N′-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)urea

Rendimiento 89.2%

Disolventes

dimethylsulfoxide

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe resulting solid was filtered
2. 2
   Otrodried under reduced pressure (54.2 mg, 89.2% yield)

Procedimiento

To 2-(4-Fluorophenoxy)ethylamine (27.4 mg, 0.18 mmol) was added a solution of (7-Hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-carbamic acid phenyl ester (50.0 mg, 0.18 mmol) in 1.5 mL dimethylsulfoxide. The mixture was stirred for 40 minutes, and then poured into water. The resulting solid was filtered and dried under reduced pressure (54.2 mg, 89.2% yield).

Fuente