Reacción #58535

Ecuación de reacción

product

1-Benzyl-4-(4-bromo-thiophen-2-yl)-pyrrolidine-3-carboxylic acid methyl ester

→

subtitle compound

1-Benzyl-4-(4-bromo-thiophen-2-yl)-pyrrolidine-3-carboxylic acid

Disolventes

HCl

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroNext, the solvent was evaporated in vacuo

Procedimiento

The product of step b) (4.3 g, 11.3 mmol) was dissolved in 6M HCl and stirred at 85° C. for 16 hours. Next, the solvent was evaporated in vacuo providing the subtitle compound that was used without further purification. MS calculated for C16H16BrNO2S−H 364, observed 364, 366.

Fuente