Reacción #58463

ord-1144f5332b1843c28d484eec61caddb4

Ecuación de reacción

CC(C)(C)OC(=O)N1CCCCC1CC(=O)O
2-(RS)-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester
[Cl-].[NH4+]
ammonium chloride
→
CC(C)(C)OC(=O)N1CCCCC1CC(N)=O
title compound
Rendimiento 46.2%
CC(C)(C)OC(=O)N1CCCCC1CC(N)=O
(RS)-2 Carbamoylmethyl-piperidine-1-carboxylic acid tert butyl ester
Rendimiento 46.2%

Reactantes

CC(C)(C)OC(=O)N1CCCCC1CC(=O)O
2-(RS)-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester
[Cl-].[NH4+]
ammonium chloride

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound (0.92 g) wvas prepared from 2-(RS)-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (2.0 g) and ammonium chloride (0.86 g) according to the method of Example 97.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07423052B2uspto-grants-2008_09