Reacción #583313

ord-d4570c1e167a437c896fca16bc29a85c

Ecuación de reacción

CC1OC(C)OC(C)O1
paraldehyde
Nc1ccccc1S(N)(=O)=O
2-Aminobenzenesulfonamide
C1CCNCC1
piperidine
Cc1ccc(S(=O)(=O)O)cc1
TsOH
→
CC1Nc2ccc(S(=O)(=O)N3CCCCC3)cc2S(=O)(=O)N1
3-Methyl-7-piperidinosulfonyl-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide

Reactantes

CC1OC(C)OC(C)O1
paraldehyde
Nc1ccccc1S(N)(=O)=O
2-Aminobenzenesulfonamide
C1CCNCC1
piperidine
Cc1ccc(S(=O)(=O)O)cc1
TsOH
—
amine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

2-Aminobenzenesulfonamide was used as starting material for the following transformation sequence: Method C, Method A (using piperidine as amine), Method D, Method G [using paraldehyde and a cat. amount of TsOH]. M.p. 255-256° C.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06943159B1uspto-grants-2005_09