Reacción #58314

ord-818fe6e421a0494398c920fefb8450e1

Ecuación de reacción

COc1ccc(Br)c(C(=O)O)c1
2-bromo-5-methoxybenzoic acid
[Li][CH2]CCC
n-butyllithium
CON(C)C(=O)c1ccc(-c2ccccc2)cc1
4-phenyl-N-methoxy-N-methylbenzamide
→
COc1ccc(C(=O)c2ccc(-c3ccccc3)cc2)c(C(=O)O)c1
2-(biphenyl-4-carbonyl)-5-methoxybenzoic acid

Reactantes

COc1ccc(Br)c(C(=O)O)c1
2-bromo-5-methoxybenzoic acid
[Li][CH2]CCC
n-butyllithium
CON(C)C(=O)c1ccc(-c2ccccc2)cc1
4-phenyl-N-methoxy-N-methylbenzamide

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThis compound is synthesized

Procedimiento

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 4-phenyl-N-methoxy-N-methylbenzamide.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07423030B2uspto-grants-2008_09