Reacción #57159

ord-33da2b59c67143d28523ed227ee1a894

Ecuación de reacción

CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(N)cc2)n1
4-[1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline
O=C=NC1CCCC1
cyclopentyl isocyanate
→
CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(NC(=O)NC3CCCC3)cc2)n1
title compound
CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(NC(=O)NC3CCCC3)cc2)n1
N-Cyclopentyl-N′-{4-[1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}urea

Reactantes

CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(N)cc2)n1
4-[1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline
O=C=NC1CCCC1
cyclopentyl isocyanate

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Following the procedure described in Example 47a with 4-[1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline and cyclopentyl isocyanate provided the title compound. ESMS [M+H]+: 415.2

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07419988B2uspto-grants-2008_09