Reacción #569493

Ecuación de reacción

water

toluene

4-chloroanthranilic acid

water

→

7-chloroisatoic anhydride

Rendimiento 101.7%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrowas changed to 500 ml flask
2. 2
   Temperaturathat the reaction temperature was maintained at 15°-25° C.

Procedimiento

According to the sa manner as in Example 3, except that the flask was changed to 500 ml flask, 70 g of water, 280 g of toluene and 35 g of 4-chloroanthranilic acid were in place of 53 g of water and 2.8 g of laurylpyridinium chloride, and that the reaction temperature was maintained at 15°-25° C., 41.0 g of 7-chloroisatoic anhydride (purity: 94%) was obtained.

Fuente