Reacción #565294

Ecuación de reacción

N-butylaniline

potassium carbonate

2-bromoheptane

DMF

→

N-butyl-N-(1-methylhexyl)aniline

Rendimiento 60.0%

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Extracciónextracted with ethyl acetate
2. 2
   LavadoThe organic phase was washed with water
3. 3
   Secadodried (MgSO4)
4. 4
   Otroevaporated

Procedimiento

A mixture of N-butylaniline (7.45 parts) anhydrous potassium carbonate (7.5 parts), 2-bromoheptane (13.5 parts) and DMF (25 parts) was stirred at 130° C. for 86 hours. The reaction mixture was poured into water, saturated with salt and extracted with ethyl acetate. The organic phase was washed with water, dried (MgSO4) and evaporated to leave N-butyl-N-(1-methylhexyl)aniline (11.8 parts, approximately 60% strength). This material had acetic anhydride (10 parts) added to it prior to further use.

Fuente