Reacción #56254

ord-5b5ac539c4354ee9821552eacc07f030

Ecuación de reacción

Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(O)C(=O)O)[C@@H](O)[C@H]1O
adenosine-5'-carboxylic acid
→
CCCCOC(=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O
adenosine-5'-carboxylic acid n-butyl ester
Rendimiento 54.0%

Reactantes

Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(O)C(=O)O)[C@@H](O)[C@H]1O
adenosine-5'-carboxylic acid

Reactivos

Ninguno

Disolventes

CCCCO
n-butanol

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

In an analogous manner, by the reaction of free adenosine-5'-carboxylic acid with ethanol, there is obtained adenosine-5'-carboxylic acid ethyl ester in a yield of 78% of theory (m.p. 204°-205° C.) and by the reaction of free adenosine-5'-carboxylic acid with n-butanol, there is obtained adenosine-5'-carboxylic acid n-butyl ester in a yield of 54% of theory (m.p. 167° C.).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04224438uspto-grants-1980_09