Reacción #554616

Ecuación de reacción

boron tribromide

p-tolyl-bis(6-methoxy-2-naphthyl)amine

→

p-tolyl-bis(6-hydroxy-2-naphthyl)amine

Disolventes

methylene chloride

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroIn a reaction vessel equipped with an agitator
2. 2
   Otrothe mixture was reacted at the same temperature for one hour
3. 3
   Otrofurther reacted for one hour
4. 4
   Extracciónextracted with ethyl acetate
5. 5
   LavadoThe organic layer was washed with water
6. 6
   Otroseparated
7. 7
   Secadoit was then dried with magnesium sulfate
8. 8
   Concentraciónsubjected to vacuum concentration
9. 9
   OtroThus, the objective product was obtained with the yield of 2.38 g

Procedimiento

In a reaction vessel equipped with an agitator, thermometer and a cooling pipe, 2.1 g of p-tolyl-bis(6-methoxy-2-naphthyl)amine and 50 mL of methylene chloride were placed. While the vessel was being cooled with ice, 12 mL of a 1M methylene chloride solution of boron tribromide was delivered by drops into the vessel, and the mixture was reacted at the same temperature for one hour. The temperature was raised to a room temperature and further reacted for one hour. Then, the reacted solution was poured into ice water and extracted with ethyl acetate. The organic layer was washed with water and separated, and it was then dried with magnesium sulfate and subjected to vacuum concentration. Thus, the objective product was obtained with the yield of 2.38 g.

Fuente