Reacción #554567

Ecuación de reacción

Phosphorus oxychloride

dimethylaniline

phenanthridine

→

9-chlorophenanthridine

Rendimiento 96.0%

Disolventes

H2O

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaby refluxing for 3 hours
2. 2
   Extracciónthe obtained solid was extracted with chloroform
3. 3
   Secadoby drying with sodium sulfate
4. 4
   FiltraciónAfter filtration
5. 5
   Otrothe filtrate was evaporated to dryness under reduced pressure
6. 6
   OtroThe obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%)

Procedimiento

Phosphorus oxychloride (15 ml) and dimethylaniline (0.63 ml) were added to phenanthridine (2.0 g), followed by refluxing for 3 hours. The solution was poured into H2O to generate a solid, and the obtained solid was extracted with chloroform, followed by drying with sodium sulfate. After filtration, the filtrate was evaporated to dryness under reduced pressure. The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%).

Fuente