Reacción #55154

Ecuación de reacción

Methyl 5-benzyl-4-oxazolecarboxylate

lithium aluminium hydride

→

5-benzyl-4-hydroxymethyloxazole

Disolventes

tetrahydrofuran

Condiciones de reacción

Procedimiento

Methyl 5-benzyl-4-oxazolecarboxylate is reduced with lithium aluminium hydride in tetrahydrofuran to give 5-benzyl-4-hydroxymethyloxazole, which on reaction with thionyl chloride is converted to 5-benzyl-4-chloromethyloxazole.

Fuente