Reacción #54985

Ecuación de reacción

2-chloro-5-trifluoromethyl-aniline

ethoxymethylenemalononitrile

→

N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline

Rendimiento 70.0%

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe mixture is refluxed for 48 hours
2. 2
   TemperaturaAfter cooling
3. 3
   Filtraciónthe precipitated product is collected by filtration
4. 4
   Lavadowashed with ethanol
5. 5
   OtroRecrystallisation from ethanol
6. 6
   Otroaffords the above product with a melting point of 166°-169° C.

Procedimiento

19.6 Parts of 2-chloro-5-trifluoromethyl-aniline and 12.2 parts of ethoxymethylenemalononitrile are dissolved in 125 parts of ethanol and the mixture is refluxed for 48 hours. After cooling, the precipitated product is collected by filtration and washed with ethanol. Recrystallisation from ethanol affords the above product with a melting point of 166°-169° C. and in a 70% yield.

Fuente