Reacción #54184

Ecuación de reacción

1(2-furyl)-1-ethanol

sodium hypochlorite

Chlorine

→

maltol

Disolventes

tetrahydrofuran

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturamaintaining the reaction temperature below 5° C
2. 2
   TemperaturaThe reaction mixture is then heated
3. 3
   Temperaturato reflux
4. 4
   Otrothe tetrahydrofuran removed by distillation
5. 5
   TemperaturaHeating
6. 6
   workup.WAITis continued for an additional hour
7. 7
   TemperaturaThe reaction mixture is cooled

Procedimiento

To a solution of 1(2-furyl)-1-ethanol (0.05 mole) in 15 ml of tetrahydrofuran and 15 ml of water at 5° C. is added 21.7 ml of 2.8 M sodium hypochlorite solution. Chlorine (0.05 mole) is added to the reaction flask via a gas inlet tube maintaining the reaction temperature below 5° C. The reaction mixture is then heated to reflux and the tetrahydrofuran removed by distillation. Heating is continued for an additional hour. The reaction mixture is cooled and maltol is isolated by the procedure described in Example 1.

Fuente