Reacción #53818

ord-b5bc525e09a04804842b7d1f8dbc3a4a

Ecuación de reacción

CN(C(=O)OC(C)(C)C)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester
BrCCCCCCCBr
1,7-dibromoheptane
→
CN(C(=O)OC(C)(C)C)[C@H]1CC[C@H](OCCCCCCCBr)CC1
trans-[4-(7-Bromo-heptyloxy)-cyclohexyl]-methyl-carbamic acid tert-butyl ester

Reactantes

CN(C(=O)OC(C)(C)C)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester
BrCCCCCCCBr
1,7-dibromoheptane

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

In analogy to examples 1.4 and 1.5, trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester was reacted with 1,7-dibromoheptane to yield trans-[4-(7-Bromo-heptyloxy)-cyclohexyl]-methyl-carbamic acid tert-butyl ester which was reacted with N-allylmethylamine to yield trans-(4-[7-(Allyl-methyl-amino)-heptyloxy]-cyclohexyl)-methyl-carbamic acid tert-butyl ester as colorless oil, MS: 397 (MH+).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06858651B2uspto-grants-2005_02