Reacción #531800

Ecuación de reacción

coronene

succinic anhydride

aluminum chloride

→

yellow-green solid

Rendimiento 88.4%

γ-oxo-4-(coronen-1-yl)butanoic acid

Rendimiento 88.4%

Disolventes

nitrobenzene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe substance obtained here
2. 2
   Otrowas immersed in an ice bath
3. 3
   Otrothe reaction container was removed from the ice bath
4. 4
   workup.ADDITION10 ml of cooled 2M hydrochloric acid was added
5. 5
   workup.WAITfollowed by 10-minute
6. 6
   workup.STIRRINGstirring
7. 7
   TemperaturaThe substance was cooled slowly down to room temperature
8. 8
   Otroto precipitate a solid substance
9. 9
   FiltraciónThe solid substance was collected by filtration
10. 10
    workup.ADDITIONThis solid substance was dispersed in 20 ml of xylene
11. 11
    Temperaturawas heated to 140° C
12. 12
    workup.DISSOLUTIONIn this manner, the solid substance was dissolved
13. 13
    TemperaturaThe substance was then cooled slowly back to room temperature
14. 14
    Otroto precipitate a solid substance
15. 15
    OtroThe solid substance obtained here
16. 16
    Filtraciónwas collected by filtration
17. 17
    Otrowas dried under reduced pressure

Procedimiento

The coronene 81 (0.699 g, 2.33 mmol) and 0.514 g (5.14 mmol) of succinic anhydride were put into a 100-ml two-inlet flask, and a nitrogen substitution was performed. The substance obtained here was immersed in an ice bath. After 2.80 g (21.0 mmol) of aluminum chloride dispersed in 20 ml of nitrobenzene was slowly dripped onto the substance, the reaction container was removed from the ice bath, and the substance was stirred at room temperature for 5 hours. After the reaction was completed, 10 ml of cooled 2M hydrochloric acid was added, followed by 10-minute stirring. The substance was cooled slowly down to room temperature, to precipitate a solid substance. The solid substance was collected by filtration. This solid substance was dispersed in 20 ml of xylene, and was heated to 140° C. In this manner, the solid substance was dissolved. The substance was then cooled slowly back to room temperature, to precipitate a solid substance. The solid substance obtained here was collected by filtration, and was dried under reduced pressure, to obtain 0.825 g of the yellow-green solid substance 82.

Fuente