Reacción #52307

Ecuación de reacción

sodium hydroxide

trimethyl-triethoxyprop-1-ynyl-silane

→

title compound

Rendimiento 55.8%

3,3,3-Triethoxypropyne

Rendimiento 55.8%

Disolventes

water

ethanol

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Extracciónthe mixture was extracted with ethyl acetate
2. 2
   SecadoThe organic extracts were dried with magnesium sulfate
3. 3
   Otrothe solvent was removed under reduced pressure

Procedimiento

A solution of sodium hydroxide (0.14 g, 3.60 mmol) in water (50 mL) was added to a solution of trimethyl-triethoxyprop-1-ynyl-silane (50.0 g, 208 mmol) in ethanol (250 mL). After stirring for 1 hour at room temperature, water was added and the mixture was extracted with ethyl acetate. The organic extracts were dried with magnesium sulfate and the solvent was removed under reduced pressure to give the title compound (20.0 g, 52% yield) as yellow oil. 1H NMR (CDCl3) δ 3.70 (q, 6H, J=8.0 Hz), 2.56 (s, 1H) 1.24 (t, 9H, J=8.0 Hz).

Fuente