Reacción #51327

Ecuación de reacción

N-(3,5-difluorophenyl)alanine

iso-butanol

→

title compound

N-(3,5-difluorophenyl)alanine iso-butyl ester

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe reaction was monitored by tlc on silica gel (Rf=0.9 in 3% methanol/methylene chloride) and purification

Procedimiento

Following General Procedure AH above and using N-(3,5-difluorophenyl)alanine (from Example AC above) and iso-butanol, the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.9 in 3% methanol/methylene chloride) and purification was by preparative plate chromatography (silica gel using 3% methanol/methylene chloride as the eluant).

Fuente