Reacción #51324

Ecuación de reacción

3,4-dichloroaniline

2-ethylbutyl pyruvate

→

title compound

N-(3,4-dichlorophenyl)alanine 2-ethylbutyl ester

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe reaction was monitored by tlc on silica gel (Rf=0.6 in 25% EtOAc/hexanes) and purification

Procedimiento

Following General Procedure AA above and using 3,4-dichloroaniline (Aldrich) and 2-ethylbutyl pyruvate (prepared by following General Procedure AO above using 2-ethylbutanol (Aldrich) in place of iso-butanol), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.6 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).

Fuente