Reacción #51317

Ecuación de reacción

2-chloro-4-fluorobenzonitrile

D,L-alanine iso-butyl ester hydrochloride

→

title compound

N-(3-chloro-4-cyanophenyl)alanine iso-butyl ester

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe product was recovered by column chromatography on silica gel using 1:5 EtOAc/hexanes as the eluant

Procedimiento

Following General Procedure AP above and using 2-chloro-4-fluorobenzonitrile (Aldrich) and D,L-alanine iso-butyl ester hydrochloride (from Example AA above), the title compound was prepared. The product was recovered by column chromatography on silica gel using 1:5 EtOAc/hexanes as the eluant.

Fuente