Reacción #50554

Ecuación de reacción

4,5-Dihydro-1-phenyl-1H-pyrazol-3-amine

4-amino-2,6-dimethylphenyl acetate

toluene-4-sulfonic acid

→

title product

Rendimiento 46.7%

4-[4,5-Dihydro-1-phenyl-1H-pyrazol-3-yl]amino-2,6-di methylphenyl acetate

Rendimiento 46.7%

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroEvaporation and chromatography (silica, dichloromethane/ethyl acetate [95:5]) of the residue

Procedimiento

4,5-Dihydro-1-phenyl-1H-pyrazol-3-amine (0.16 g), 4-amino-2,6-dimethylphenyl acetate (0.2 g), and toluene-4-sulfonic acid (0.02 g) were refluxed in toluene under nitrogen for 8 hours. Evaporation and chromatography (silica, dichloromethane/ethyl acetate [95:5]) of the residue gave the title product (0.15 g), as a solid.

Fuente