Reacción #502151

Ecuación de reacción

2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

N-methylpiperazine

→

title compound

2-(3-Chlorobenzyl)-4-(4-methylpiperazin-1-yl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

Condiciones de reacción

Procedimiento

In analogy to the preparation of Example 1, 100 mg (0.34 mmol) of 2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 343 mg (3.43 mmol) of N-methylpiperazine to give 101 mg (84% of theory) of the title compound.

Fuente