Reacción #4855

Ecuación de reacción

2,3-dihydro-5,7-dinitro-2-methyl-benzofuran

methylamine

→

1-(2-methylamino-3,5-dinitrophenyl)-2-propanol

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaAfter the mixture is cooled
2. 2
   Otrothe expected product precipitates
3. 3
   Lavadowashed with alcohol
4. 4
   Otrorecrystallized from 50 ml of 96° strength ethanol
5. 5
   OtroAfter being dried
6. 6
   Otro0.047 mole (12 g) is obtained of a product which melts at 132° C.

Procedimiento

0.056 Mole (12.5 g) of 2,3-dihydro-5,7-dinitro-2-methyl-benzofuran is suspended in 100 ml of a 33% strength solution of methylamine in ethanol. After 10 hours' stirring at room temperature in a sealed Erlenmeyer, the reaction mixture is brought for 30 minutes to the refluxing temperature of the alcohol. After the mixture is cooled, the expected product precipitates. It is drained, washed with alcohol and then recrystallized from 50 ml of 96° strength ethanol. After being dried, 0.047 mole (12 g) is obtained of a product which melts at 132° C.

Fuente