Reacción #482014

Ecuación de reacción

AIBN

H2SO4

hydrobromic acid

3,6-dichloro-1,2-xylene

hydrogen peroxide

→

3,6-dichloro-2-methylbenzyl Bromide

Disolventes

chlorobenzene

Condiciones de reacción

Tratamiento posterior

1. 1
   Lavadowashed twice with 400 ml of water and once with 400 ml of saturated sodium bicarbonate solution
2. 2
   workup.DISTILLATIONthe chlorobenzene is then distilled off

Procedimiento

170.1 g (0.97 mol) of 3,6-dichloro-1,2-xylene are initially charged in 1180 ml of chlorobenzene, and 4.9 g of conc. H2SO4 and 203.1 g (1.18 mol) of 47% strength hydrobromic acid are added. The mixture is heated to 70° C., and 0.9 g of AIBN are added. Over a period of 5 h, 353.7 g (1.04 mol) of a 10% strength solution of hydrogen peroxide are added at 70-75° C., the mixture is stirred at 70-75° C. for 30 min, washed twice with 400 ml of water and once with 400 ml of saturated sodium bicarbonate solution, and the chlorobenzene is then distilled off.

Fuente