Reacción #481681

Ecuación de reacción

4-Hydroxypiperidine

potassium carbonate

1-iodoheptane

→

1-Heptyl-4-hydroxypiperidine

Disolventes

N,N-dimethylformamide

ethyl acetate

Condiciones de reacción

Tratamiento posterior

1. 1
   Lavadowashed with water, brine
2. 2
   Otrodried
3. 3
   Otroevaporated

Procedimiento

4-Hydroxypiperidine was dissolved in N,N-dimethylformamide (20 ml) and treated with potassium carbonate (1.5 g, 10.8 mmol) and 1-iodoheptane (1.8 ml, 11.3 mmol). After stirring for 2 h the mixture was diluted with ethyl acetate, washed with water, brine, dried and evaporated.

Fuente