Reacción #4808

Ecuación de reacción

p-n-dodecylaniline

acetic anhydride

acetic anhydride

→

above-named material

N-Acetyl-4-n-dodecylaniline

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroIn a 1-liter flask fitted with a stirrer
2. 2
   Temperaturareflux condenser
3. 3
   workup.DISSOLUTIONdissolved in 138 ml of tolune
4. 4
   Otrorises from 40° to 80° C
5. 5
   TemperaturaThe reaction mixture is then cooled
6. 6
   Otroto yield the crude product which
7. 7
   Otrois recrystallized from 800 ml of methanol

Procedimiento

In a 1-liter flask fitted with a stirrer and reflux condenser is added 137.5 grams (0.525 mole) of p-n-dodecylaniline, dissolved in 138 ml of tolune. To this is added over a 15-minute period 57.5 ml of acetic anhydride. The temperature rises from 40° to 80° C. After all the acetic anhydride is added, the reaction mixture is stirred at 40° C. for 3 hours. The reaction mixture is then cooled to yield the crude product which is recrystallized from 800 ml of methanol to give 151.1 grams of the above-named material as a solid melting at 100°-102° C.

Fuente