Reacción #4801

ord-5eae9c249c2f4d548c00c56de8b74d45

Ecuación de reacción

Cc1cccc2c1C(=O)N1CCC[C@H]1C(=O)N2
(S)-6-methyl-1,2,3,11a-tetrahydro-5H-pyrrolo (2,1-c) (1,4) benzodiazepine-5,11 (10H)-dione
O=C(O)[C@@H]1CCCN1
L-proline
→
COc1cccc2c1C(=O)N(C)CC(=O)N2
6-methoxy-3,4-dihydro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dione

Reactantes

Cc1cccc2c1C(=O)N1CCC[C@H]1C(=O)N2
(S)-6-methyl-1,2,3,11a-tetrahydro-5H-pyrrolo (2,1-c) (1,4) benzodiazepine-5,11 (10H)-dione
O=C(O)[C@@H]1CCCN1
L-proline

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

(S)-6-methyl-1,2,3,11a-tetrahydro-5H-pyrrolo (2,1-c) (1,4) benzodiazepine-5,11 (10H)-dione by reaction with L-proline. M.p. 207.6°-209.9° C.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04727153uspto-grants-1988_02