Reacción #470419

Ecuación de reacción

4′,7-Dihydroxyisoflav-3-ene

ethanol

4-Chlorobenzylamine

formaldehyde

→

title compound

Rendimiento 88.0%

4-(3-(4-Chlorobenzyl)-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

Rendimiento 88.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe white precipitate was collected

Procedimiento

4′,7-Dihydroxyisoflav-3-ene (506 mg, 2.11 mmol) was dissolved in ethanol (8 ml). 4-Chlorobenzylamine (0.33 ml, 2.70 mmol) was added followed by formaldehyde solution (2 ml, 0.03 mol, 37% wt.). The reaction was stirred at room temperature for 4 days. The white precipitate was collected to afford the title compound (748 mg, 88%).

Fuente