Reacción #470369
ord-0b519d05882442eeb1c0ab17562a45fa
Ecuación de reacción
trifluoromethanesulfonic acid
N-methoxymethyl-N-methylpyrrolidinium chloride
N-Methoxymethyl-N-Methylpyrrolidinium Chloride
→
trifluoromethanesulfonic acid
desired product
N-Methoxymethyl-N-Methylpyrrolidinium
Reactantes
Reactivos
Ninguno
Condiciones de reacción
Temperatura
130°CELSIUS
Condiciones detalladas
See reaction.notes.procedure_details.
Tratamiento posterior
- 1Otroto remove hydrogen chloride
- 2Otroproduced as a by-product
Procedimiento
A 30.0 g quantity of N-methoxymethyl-N-methylpyrrolidinium chloride prepared in Example 10 was dissolved in 30.0 g of MeOH, and 80.0 g of methanol solution of 35 wt. % trifluoromethanesulfonic acid was added to the solution. The mixture was heated at 130° C. in a nitrogen stream to remove hydrogen chloride produced as a by-product, an excess of trifluoromethanesulfonic acid and methanol, giving 49.0 g of the desired product.