Reacción #470368

Ecuación de reacción

sodium acetate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Acetate

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe mixture was reacted at room temperature for 1.5 hours
2. 2
   Otrowhereby the reaction was terminated
3. 3
   FiltraciónThe reaction mixture was filtered
4. 4
   Concentraciónthe filtrate was concentrated
5. 5
   Otrodried in a vacuum
6. 6
   workup.ADDITIONTo the residue was added 100 ml of dichloromethane
7. 7
   Filtraciónfollowed by filtration with a membrane
8. 8
   Filtraciónfilter
9. 9
   Concentraciónconcentration in a vacuum
10. 10
    Otrodrying

Procedimiento

A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.

Fuente