Reacción #470364

Ecuación de reacción

sodium carbonate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Carbonate

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe mixture was reacted at room temperature for 0.5 hour
2. 2
   Otrowhereby the reaction was terminated
3. 3
   ConcentraciónThe reaction mixture was concentrated
4. 4
   Secadodried in vacuum, and 100 ml of ethyl alcohol
5. 5
   workup.ADDITIONwas added to the residue
6. 6
   Otroto remove insoluble sodium chloride
7. 7
   workup.DISSOLUTIONThe resulting product was dissolved in dichloromethane
8. 8
   Filtraciónthe solution was filtered with a membrane
9. 9
   Filtraciónfilter again
10. 10
    Concentraciónthe filtrate was concentrated in a vacuum
11. 11
    Otrodried

Procedimiento

A 1.60 g quantity of sodium carbonate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 18 g of deionized water, and 5.01 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 0.5 hour, whereby the reaction was terminated. The reaction mixture was concentrated and dried in vacuum, and 100 ml of ethyl alcohol was added to the residue to remove insoluble sodium chloride. The resulting product was dissolved in dichloromethane, the solution was filtered with a membrane filter again, and the filtrate was concentrated in a vacuum and dried, giving 5.41 g of the desired product.

Fuente