Reacción #46930

Ecuación de reacción

2-Fluorobenzaldehyde

but-3-en-2-one

p-piperidinylsulfonyl phenylamine

→

titled compound

1-{4-[2-(2-fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine

Condiciones de reacción

Procedimiento

2-Fluorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-piperidinylsulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 1.50 (6H), 2.21 (3H), 2.85 (4H), 6.15 (1H), 6.25 (1H), 7.03-7.90 (8H); MS (ESI) m/z 399 (M+H).

Fuente