Reacción #467901

Ecuación de reacción

hydrogen chloride

3,5 dinitrobenzoic acid

thionyl chloride

dinitrobenzoic acid

→

3,5-dinitrobenzoic chloride

Rendimiento 90.0%

Disolventes

ethyl acetate

DMF

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrothe reaction mixtures
2. 2
   Temperaturawere refluxed
3. 3
   ConcentraciónThe reacted solution was concentrated until a solid
4. 4
   Otrocould be precipitated
5. 5
   workup.ADDITIONwas poured into hexane
6. 6
   Otrothe precipitated solid was separated by filtration

Procedimiento

3,5 dinitrobenzoic acid and ethyl acetate were placed in a reaction vessel. While thionyl chloride with some drops of DMF (about double as many moles as dinitrobenzoic acid) was dropped into the reaction mixtures, the reaction mixtures were refluxed with stirring until the generation of hydrogen chloride gas stopped. The reacted solution was concentrated until a solid could be precipitated and was poured into hexane and then the precipitated solid was separated by filtration. 3,5-dinitrobenzoic chloride was obtained in a 90% yield.

Fuente