Reacción #46580

ord-8dc5740280304c388f3887edea09d7f4

Ecuación de reacción

COC(=O)c1ccc2cc[nH]c2c1
methyl indole-6-carboxylate
CCOC(=O)c1cc2ccccc2[nH]1
ethyl indole-2-carboxylate
COC(=O)c1ccc2ccn(C)c2c1
title compound
Rendimiento 95.0%
COC(=O)c1ccc2ccn(C)c2c1
Methyl 1-methyl-1H-indole-6-carboxylate
Rendimiento 95.0%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

According to the procedure of Preparation 9 (a), except substituting methyl indole-6-carboxylate for the ethyl indole-2-carboxylate, the title compound (2.5 g, 95%) was obtained as white solid: MS (ES) m/e 190.2 (M+H)+.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07741339B2uspto-grants-2010_06