Reacción #460019

Ecuación de reacción

ethyl acrylate

1-(4-chlorobenzyl)-piperazine

→

ethyl 3-[4-(4-chlorobenzyl)-piperazin-1-yl]-propionate

Rendimiento 92.8%

Disolventes

ethanol

Condiciones de reacción

Procedimiento

Analogously to Example 1a, 30 g (0.3 mol) ethyl acrylate and 63.2 g 1-(4-chlorobenzyl)-piperazine are reacted in 200 ml ethanol to give 86.5 g (92.8% of theory) ethyl 3-[4-(4-chlorobenzyl)-piperazin-1-yl]-propionate; b.p. 150° - 160° C./0.1 mm Hg.

Fuente