Reacción #459271

Ecuación de reacción

9-anthroic acid

thionyl chloride

→

9-anthroyl chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturais heated
2. 2
   Temperaturaunder reflux for 1 hour
3. 3
   OtroThe excess thionyl chloride is removed under vacuum (30 mm; 90° bath temperature)
4. 4
   workup.ADDITION50 ml of toluene is added
5. 5
   Concentraciónthe mixture is concentrated again

Procedimiento

The 2-methyl-3,5-dihydro-5,9b-o-benzenobenz[e]isoindol-1-(2H)-one starting material was prepared as follows: a mixture of 25 g of 9-anthroic acid and 75 ml of thionyl chloride is heated under reflux for 1 hour. The excess thionyl chloride is removed under vacuum (30 mm; 90° bath temperature); 50 ml of toluene is added and the mixture is concentrated again. This operation is repeated once more to give 28.3 g of 9-anthroyl chloride as a very moisture-sensitive, yellow solid.

Fuente