Reacción #457136

Ecuación de reacción

3-ethyl-2-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride

isopropanol-HCl

→

title compound

Rendimiento 192.2%

7-Amino-3-ethyl-2-methyl-1,2,3,4-tetrahydroisoquinoline Dihydrochloride

Rendimiento 192.2%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe catalyst was removed by filtration
2. 2
   Otrothe solvent evaporated

Procedimiento

To a pressure bottle charged with 3-ethyl-2-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride (3.6 g, 17 mmols) dissolved in methanol (100 ml) and saturated isopropanol-HCl (20 ml) was added 10% Pd--C (250 mg), and the reaction was hydrogenated for 1 h. The catalyst was removed by filtration and the solvent evaporated to give the title compound (4.3 g).

Fuente