Reacción #452430

ord-8ae4c1cbb2f44f23852ec10903d48b5b

Ecuación de reacción

O=C(O)Cc1ccccc1Cl
o-chlorophenyl-acetic acid
O=S(Cl)Cl
thionyl chloride
O=C(Cl)Cc1ccccc1Cl
o-chloro-phenylacetyl chloride
Rendimiento 99.0%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThe volatiles were then removed in vacuo

Procedimiento

A mixture of 30.0 gm (0.176 mole) of o-chlorophenyl-acetic acid and 40.0 mL of thionyl chloride was stirred at ambient temperature for 18 hours. The volatiles were then removed in vacuo to give 32.76 gm (99.0 %) of o-chloro-phenylacetyl chloride as a transparent, pale yellow, mobile liquid.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06126932uspto-grants-2000_10