Reacción #452424

Ecuación de reacción

N-(4-fluorobenzoyl)-4-nitroaniline

→

N-(4-fluoro-benzoyl)-4-aminoaniline

Rendimiento 79.0%

Disolventes

tetrahydrofuran

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe reaction mixture was then filtered
2. 2
   Concentraciónthe filtrate concentrated under reduced pressure

Procedimiento

A mixture of 32.25 gm (124 mMol) N-(4-fluorobenzoyl)-4-nitroaniline and 3.2 gm platinum on carbon in 500 mL tetrahydrofuran was hydrogenated at room temperature for 18 hours with an initial pressure of 60 p.s.i. The reaction mixture was then filtered and the filtrate concentrated under reduced pressure to give 22.45 gm (79%) of N-(4-fluoro-benzoyl)-4-aminoaniline.

Fuente