Reacción #452414

Ecuación de reacción

n-butyl bromide

NaHCO3

m-aminophenol

→

3-(n-butylamino)phenol

Rendimiento 57.0%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe mixture is refluxed for 5 h
2. 2
   TemperaturaAfter cooling
3. 3
   Filtraciónit is filtered
4. 4
   Otrothe solvent is removed in vacuo

Procedimiento

0.11 mol of n-butyl bromide and 0.1 mol NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-butylamino)phenol.

Fuente