Reacción #45198

Ecuación de reacción

4-nitro-L-phenylalanine

2,6-dichlorobenzoylchloride

sodium hydroxide

→

Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine

Disolventes

acetone

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroat 5 to 15° C.
2. 2
   Otrocrystallization

Procedimiento

Concretely, 4-nitro-L-phenylalanine and 2,6-dichlorobenzoylchloride are condensed in a mixed solvent of a sodium hydroxide aqueous solution and acetone with keeping the reaction temperature at 5 to 15° C., and then crystallization is conducted to obtain a corresponding condensed substance, Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine almost quantitatively.

Fuente