Reacción #450989

ord-86053d540300417b91824d235673d37d

Ecuación de reacción

CC(C)(C)N
Tertiary butyl amine
O=C(O)CNCP(=O)(O)O
glyphosate
CC(C)(C)N(CC(=O)O)CP(=O)(O)O
N-t-butyl-N-phosphonomethylglycine
→
CC(C)(C)NCC(=O)O
N-t-butylglycine

Reactantes

—
bromoacetate ester
CC(C)(C)N
Tertiary butyl amine
O=C(O)CNCP(=O)(O)O
glyphosate
—
esters
CC(C)(C)N(CC(=O)O)CP(=O)(O)O
N-t-butyl-N-phosphonomethylglycine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Gaertner, U.S. Pat. No. 3,927,080, describes the production of glyphosate by acid hydrolysis and dealkylation of N-t-butyl-N-phosphonomethylglycine or its esters. Tertiary butyl amine is reacted with a bromoacetate ester to produce an ester of N-t-butylglycine, which is in turn reacted with formaldehyde and phosphorous acid to produce the N-t-butyl-N-phosphonomethylglycine precursor.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05874612uspto-grants-1999_02