Reacción #4475

Ecuación de reacción

1,3-Cyclohexanedione

4-methoxyphenylhydrazine hydrochloride

→

title compound

Rendimiento 48.7%

1,2,3,9-Tetrahydro-6-methoxy-4H-carbazol-4-one

Rendimiento 48.7%

Disolventes

ethanol

water

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaat reflux for 14 h
2. 2
   TemperaturaOn cooling to ambient temperature
3. 3
   Otroto give a solid, which
4. 4
   Otrowas dried in vacuo

Procedimiento

1,3-Cyclohexanedione (8 g) was added to a solution of 4-methoxyphenylhydrazine hydrochloride (10 g) in ethanol (350 ml) and water (70 ml). The resulting solution was stirred at room temperature for 3 h and then at reflux for 14 h. On cooling to ambient temperature, the reaction mixture was poured into water (3 l) to give a solid, which was dried in vacuo to give the title compound, (6.0 g) m.p. 279°-279.5°.

Fuente