Reacción #446719

Ecuación de reacción

2-aminobenzamide

2-methylbenzoyl isothiocyanate

→

desired product

Rendimiento 95.8%

N-[[[2-(Aminocarbonyl)phenyl]amino]thioxomethyl]-2-methylbenzamide

Rendimiento 95.8%

Disolventes

ether

ether

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwas added dropwise
2. 2
   Otrothe solid was collected

Procedimiento

To a stirred mixture of 4.9 g of 2-aminobenzamide and 200 ml of ether was added dropwise, a solution of 6.67 g of 2-methylbenzoyl isothiocyanate in 100 ml of ether over 15 minutes After a few hours, the solid was collected, giving 10.8 g of the desired product as grey crystals, mp 181°-185° C. (dec.).

Fuente