Reacción #446710

Ecuación de reacción

4-chlorobenzoyl isothiocyanate

2-aminobenzamide

→

desired product

Rendimiento 85.8%

N-[[[2-(Aminocarbonyl)phenyl]amino]thioxomethyl]-4-chlorobenzamide

Rendimiento 85.8%

Disolventes

tetrahydrofuran

tetrahydrofuran

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwas added
2. 2
   Otrothe solid was collected

Procedimiento

To a stirred mixture of 10.5 g of 4-chlorobenzoyl isothiocyanate in 100 ml of tetrahydrofuran was added a mixture of 6.8 g of 2-aminobenzamide in 200 ml of tetrahydrofuran. After stirring for 3 hours, the solid was collected, giving 14.3 g of the desired product as grey crystals, mp 204°-206° C. (dec.).

Fuente